منابع مشابه
Sterol synergism in yeast.
Sterol synergism as previously observed [Dahl, C.E., Dahl, J.S. & Bloch, K. (1980) Biochemistry 19, 1462-1467] and defined as a greater-than-additive growth response to pairs of sterols by Mycoplasma capricolum [Dahl, J.S., Dahl, C.E. & Bloch, K. (1981) J. Biol. Chem. 256, 87-91] is now demonstrated in the yeast mutant GL7, which is auxotrophic for sterol and unsaturated fatty acid. Mutant cell...
متن کاملPredicting transcription factor synergism.
Transcriptional regulation is mediated by a battery of transcription factor (TF) proteins, that form complexes involving protein-protein and protein-DNA interactions. Individual TFs bind to their cognate cis-elements or transcription factor-binding sites (TFBS). TFBS are organized on the DNA proximal to the gene in groups confined to a few hundred base pair regions. These groups are referred to...
متن کاملClarification: chemical synergism.
several scientists held the hope that the "Maltoni" work would clarify questions about MTBE's carcinogenic potential. Despite the enthusiasm of some scientists for Belpoggi's results, the most cursory examination of the paper reveals critical issues that show the data have been grossly overinterpreted. Rather than predicting a health hazard, the data indicate that rats tolerate enormous daily o...
متن کاملBiologic synergism and parallelism.
In epidemiologic studies of two binary exposure factors, much attention has been given to the concept of synergism of the factors. The leading dictionary of epidemiology offers two definitions of synergism, one of which this author labels statistical and the other biologic. The epidemiologic literature has been largely concerned with statistical synergism, which is typically measured using addi...
متن کاملSynergism and Drug-receptor.
a Drugs A and B have similar activity. a -l When the effective doses of A and B in combination are located in the area of m+n 1, m> 1, n> 1, they are called par tial antagonism. a -4 When they are located out of the square area, that is, m)1...
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ژورنال
عنوان ژورنال: Reviews on Clinical Pharmacology and Drug Therapy
سال: 2012
ISSN: 2542-1875,1683-4100
DOI: 10.17816/rcf102113